A Research Associate position is available within the Division of Cell & Molecular Biology within the Infection and Immunology section. The selected candidate will be based at the South Kensington Campus of Imperial College London. The Research Associate position is based in the laboratory of Dr. Gloria Rudenko in the Sir Alexander Fleming Building, at the South Kensington Campus, Imperial College London.

Project Description

The research programme studies molecular mechanisms mediating immune evasion in African trypanosomes (causative agent of African Sleeping Sickness). Trypanosomes are single-celled eukaryotes capable of continuously changing their Variant Surface Glycoprotein (VSG) coat during the course of a chronic infection. Trypanosomes provide a very manipulable experimental system for investigating antigenic variation and host-pathogen interactions. We are attempting to understand how immune evasion operates through molecular approaches including genetic modification (gene knock-outs) and double-stranded RNA inhibition (RNAi).

Requirements for the Research Position

The successful candidate must hold a PhD in Biochemistry or Molecular Biology or equivalent level of professional qualifications and experience. You will have experience in investigating basic molecular biology questions in any experimental system. You must be familiar with at least some of the following techniques: sterile cell culture and transfection, DNA cloning, DNA and RNA analysis, Nucleic acid and protein analysis through Northern, Southern and Western blotting, PCR, immunofluorescence microscopy and flow cytometry.

The candidate must have experience of working in a team, the ability to develop and apply new concepts and have a creative approach to problem-solving. You must also have excellent verbal and written communication skills and be able to write clearly and succinctly for publication.

This is a fixed term position available immediately for up to 24 months in the first instance.

Application Procedure

For details on application please follow the link to Imperial College London webpage.

Should you have any queries please contact:
Coralie Simmons - c.simmons@imperial.ac.uk

Note, application deadline to the Research Associate Cell and Molecular Biology, Imperial College London is 18 October, 2011.

Please mention scholarships4phd.blogspot.com on your application while applying for this scholarship.

© 2011 Research Grants.

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